Limitations Associated With Use of Allografts and Autografts to Bring Orthobiologics at Forefront

Orthobiologics primarily entails the use of biochemistry and biology; it refers to the branch of science that develops tissue and bone replacement materials in order to provide quick recovery and fast healing of broken bones, injured muscles, tendons and ligaments. The art and science of orthobiologics enhance the natural ability of the body to heal itself. In addition, orthobiologics utilize advanced medical technologies and stem cells for repairing and healing orthopedic injuries. This technology has aided the accelerated recovery of a number of sportspersons having orthopedic injuries. 

Transparency Market Research (TMR), a market intelligence company, throws light on the overall market for orthobiologics and answers a series of questions covering all the key attributes related to the orthobiologics market

Q. What factors will drive the growth of the orthobiologics market in the coming years? Which is the prime factor amongst them?

The prime factor fuelling the growth of the market is the increasing count of certain limitations associated with the usage of allografts and autografts. The key concerns related with the usage of allografts is the increasing risk of disease transmission and the decline in the availability of allografts. On the other hand, though autografts are the gold standard for carrying out orthopedic procedures, there are major drawbacks of using autografts such as the additional surgery involved and donor site morbidity. Hence, to overcome these disadvantages of allografts and autografts, bone graft substitutes are being utilized for performing orthopedic surgeries, hence boosting the growth of the orthobiologics market.

In addition, the rising count of sports injuries, the increasing count of orthopedic surgeries, and the increasing demand for cutting-edge products are also some of the key factors propelling the growth of the market for orthobiologics. Furthermore, the rising geriatric population and the increasing occurrence of chronic arthritis globally will also driver the growth of the market.

Q. Which is the most common orthobiologic treatment utilized and why? What are the top application areas of orthobiologics technology?

The most common orthobiologic treatment utilized is platelet-rich plasma (PRP) therapy. This therapy is a holistic approach utilized for speeding up the healing and regeneration of tendon, muscular injuries, and ligament, and lowering the time of recovery. This method has been utilized since the 1990s for assisting the healing of spinal injuries and facilitating recovery post a plastic surgery. This therapy garnered international attention in 2008 when it was utilized for the treatment of Tiger Woods, an American professional golfer and one of the highest paid athletes in the world, during his rehabilitation after micro-fracture surgery.

The key application areas of orthobiologics technology are reconstructive surgery, trauma, and spinal fusion. Amongst these, the segment of spinal fusion led the market in 2013 due to the rising count of spinal fusion surgeries, increasing occurrence of arthritis, the increasing demand for minimally invasive procedures, and the rising occurrence of obesity globally.

Q. What is the latest innovation in orthobiologics technology?

There are several innovative products and treatments that will steer the market toward a healthy future. But one that stands out is a new magnesium-based bone void filler product, named OsteoCrete™, slated to be launched by Bone Solutions Inc. (BCI) by October 2016. This product will be utilized for long-bone as well as orthopedic applications and has been approved by the FDA. OsteoCrete™ is easily assimilated back in the body, is resorbable, moldable, non-toxic, and osteoconductive in nature. It will be utilized to overcome the deficiencies found in commonly-utilized calcium-based bone void fillers as well as cements which may result in low surgery success rates.

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